MyBioSource.com's CAPG Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot. The CAPG Antibody was generated using CAPG as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Subunit Structure: Interacts with NUP62 (PubMed:18266911). Interacts with NUTF2 and RAN; involved in CAPG nuclear import (PubMed:18266911).
Post-translational Modifications: The N-terminus is blocked.
Similarity: Belongs to the villin/gelsolin family